Wow that's all over the place!
Yeah, but unlike that old channel "The Loft" (defunct?), he sticks with contemporary pop/rock. He doesn't throw in any jazz, classical, country, or hip-hop, just for the purpose of being diverse. Everything he plays, he likes (and hopefully, so do we).
And as a music expert, he throws-in a lot of interesting facts. Like before playing Cornflake Girl by Tori Amos, he went into the whole thing about drummer Matt Chamberlain, and all the bands he's played in. He talks about songs that have a lot of key changes, or where the bass line never changes (like Crazy by Seal). Or how Mandolin Rain by Bruce Hornsby is a half-shuffle, half-straight rhythm. And he's met and played with a lot of artists.
I listened to Life with John Mayer for a second evening. It makes for a nice summer sunset channel. Filling in for the Wine Bar
The channel is programmed in a way that changes from day to day. Like that playlist I posted is heavy on 70s soft rock, but sometimes he plays a lot of newer indie music, or singer-songwriter stuff, or guitar god songs, or he'll mix-in a lot of female pop singers.
And I'm always hearing a song that I haven't heard on the radio in years, like Heartbeat City by The Cars or Home by the Sea by Genesis (from the playlist I just posted). Occasionally, I'm not into a particular song they play, but I stick with it, and it pays off.